Homocysteine

Homocysteine is a building block of protein. It is not a fat. High levels are irritating to blood vessels and can lead to hardening of the arteries. Elevated homocysteine is linked to heart disease, stroke, and poor circulation in the legs.

What causes a build-up?

High levels tend to be inherited. Lack of certain vitamins in the diet, such as folic acid, can also lead to elevations.

Is homocysteine measured as part of "routine" blood work or cholesterol tests.

No.

What is a desirable level?

Levels less than 10 are desirable. Values over 10 are linked to a higher risk of heart disease and stroke.

How can a high homocysteine level be treated?

The best treatment is the vitamin folic acid, as well as vitamins B6 and B12. Minimal elevations might be treated with higher intake of foods rich in these vitamins or a multivitamin.

Foods rich in folic acid are: green leafy vegetables, orange juice, tomatoes, vegetables, and grains. Foods high in B6 include: brown rice, corn, avocados, bananas, poultry, and fish. B12 is found in poultry, fish and milk.